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. 2016 Sep 15;27(1):17–27. doi: 10.1002/hipo.22650

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© 2016 The Authors Hippocampus Published by Wiley Periodicals, Inc.

This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial‐NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.

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The graphs display the sucrose consumption data of the animals that were used for the quantitative histopathological and electron microscopic analysis. The sucrose consumption test was used to demonstrate the hedonic‐anhedonic behavior of the animals. Control rats gradually increased their sucrose intake indicating a healthy hedonic behavior. In contrast, the stressed animals progressively reduced their sucrose which indicates anhedonic behavior. Since anhedonia is a core feature of depression thus, this test demonstrates the depressive‐like behavior of the animals. The baseline sucrose consumption was defined as the mean sucrose consumption during three sucrose tests conducted before stress initiation. Statistics: one‐way ANOVA, followed by Dunnets's multiple comparison test in which the results are compared to the baseline consumption of the same group. *P < 0.05, versus the baseline value of the same group. [Color figure can be viewed at wileyonlinelibrary.com]