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. 2016 Oct 19;65(1):138–149. doi: 10.1002/glia.23083

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© 2016 The Authors. Glia Published by Wiley Periodicals, Inc.

This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.

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Conserved microglia functions in the zebrafish. (A) Ingenuity pathway analysis (IPA) canonical pathways most significantly enriched in zebrafish microglia. (B) Heatmap showing expression Z‐scores of immune genes significantly higher expressed in microglia than other brain cells (FDR <0.01 and logFC >1). (C) CPM values of zebrafish orthologs of genes involved in synaptic pruning in microglia and brain samples. Values in (C) represent mean of three independent experiments; Error bars in (C) represent standard deviation. TLR, Toll‐like receptors; PR, purinergic receptors; AP, antigen presentation; IL, interleukins + interleukin receptors; CP, complement.