Fig 2. Extracts derived from R03 and ST1 diets induce different cytokine production from dendritic cells.

Bone marrow-derived dendritic cells (BM-DC) generated from wild-type (WT, white bars) and TLR4-deficient (TLR4-/-, black bars) mice were cultured with media alone (M), ultra-pure lipopolysaccharide from E. coli (LPS, 1 μg/ml), extract of R03 (eR03, 100 μg/ml) or of ST1 (eST1, 100 μg/ml) for 18 h. Production of IL-12p70 (A), IL-10 (B), TNF-α (C) and IL-6 (D) in culture supernatants was measured by ELISA. Mean values ± SEM are shown. One representative out of three experiments yielding similar results is shown.