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. 2016 Dec 16;12(12):e1005283. doi: 10.1371/journal.pcbi.1005283

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© 2016 Bentley et al

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Fig 5 — (A) Rich-club curve for the directed monoamine network. Dashed line indicates the rich-club coefficient for the C. elegans monoamine network and the solid curve is a randomized rich-club curve representing the average rich-club coefficient of 100 random graphs (preserving degree distribution) at each value k. Individual rich-club neurons are shown in Table 3. (B) Schematic showing the separate aminergic systems and the volume transmission signalling between them based on receptor expression. Arrows between boxes denote connections between all of the contained neurons. (C) Hive plot showing the connections made by individual monoamines. Nodes are classified as sensory, motor or interneurons and are arranged along the three axes according to their degree. Hubs are located further out along the axes. (D) Connections between the wired & monoamine rich-clubs. Aminergic rich-club neurons are represented as grey octagons. Members of the wired rich-club are shown as circles (RIBL but not RIBR is included due to its higher synaptic degree). Dashed red lines are extrasynaptic links. Solid black lines are chemical or electrical synapses.