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. 2017 Jan 4;12(1):e0167609. doi: 10.1371/journal.pone.0167609

Table 4. Estimated differences between treatment groups and placebo in physician evaluations of nausea based on available summary information for analyzed participants.

Allocated n = 2308 Excluded, estimated missing (%) n = 709 (31%) Analyzed n = 1599 reported percent improved Absolute difference in % improved versus placebo (95% CI)
doxylamine/pyridoxine/dicyclomine 288 99 (34%) 189 71 14 (3.8 to 24)
doxylamine/pyridoxine 284 71 (25%) 213 78 21 (11 to 30)
dicyclomine/doxylamine 301 83 (28%) 218 78 21 (11 to 30)
doxylamine 287 78 (27%) 209 77 20 (10 to 29)
dicyclomine/pyridoxine 286 91 (32%) 195 61 4 (-6 to 14)
pyridoxine 290 99 (34%) 191 66 9 (-1.3 to 19)
dicyclomine 286 83 (29%) 203 61 4 (-6 to 14)
placebo 286 105 (37%) 181 57 -