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. Author manuscript; available in PMC: 2017 Jun 1.
Published in final edited form as: N Engl J Med. 2016 Dec;375(22):2165–2176. doi: 10.1056/NEJMoa1509164

Figure 1. Clinical Findings.

Figure 1

Panel A shows the features of the patient (shown with informed consent). The image on the left shows increased intraorbital distance, short palpebral fissures, abnormal nasal creases, and micrognathia; the image on the right shows ear tag, loose skin folds, and hirsutism. Panel B shows the percentage of peripheral-blood chimerism after infusions of hematopoietic stem cells (red arrows) from a matched unrelated donor. Chimerism has been stable for more than 2 years. Panel C shows T-cell–receptor diversity measured by spectratyping before and 6 months after hematopoietic stem-cell transplantation. Numbers in the upper left of each panel indicate the specific T-cell–receptor Vβ gene family analyzed.