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. Author manuscript; available in PMC: 2017 Dec 1.
Published in final edited form as: Trends Mol Med. 2016 Nov 17;22(12):1060–1076. doi: 10.1016/j.molmed.2016.10.008

Figure I. Schematic of the Stages of Canonical Macroautophagy.

Figure I

(1) Induction/initiation, (2) elongation, (3) substrate targeting, and (4) maturation/lysosomal fusion and targeting of bacterial pathogens (substrate targeting) as detailed in Box 2.