Skip to main content
. Author manuscript; available in PMC: 2017 Jan 6.
Published in final edited form as: Genes Immun. 2016 May 12;17(5):298–304. doi: 10.1038/gene.2016.21

Table 3.

Population allele frequency and statistical power

Phenotype Locus SNP OR Case MAF Cases (n) Control MAF Controls (n) Population MAFa Power (%)c
WNND TFCP2L1 rs11122852 3.57 0.0328 609 0.0094 954 0.0079 99
rs7563166 3.58 0.0222 609 0.0063 954 0.0079 96
rs6756142 3.91 0.0222 609 0.0058 954 0.0079 97
Encephalitis CACNA1H rs78879053 37.88 0.0133 225 0.0004 954 0.003b 96
CACNA1H rs113802594 5.40 0.0133 225 0.0025 954 0.005b 84
OFCC1 rs72653717 NA 0.0067 225 0.0000 954 0b NA
AFP TFCP2L1 rs11122852 4.94 0.0449 267 0.0094 954 0.0079 100
rs7563166 4.88 0.0300 267 0.0063 954 0.0079 99
rs6756142 4.30 0.0243 267 0.0058 954 0.0079 95
a

CEU and GBI populations, 1000 Genomes Phase 3 release

b

Shown are MAF for European populations as MAF was 0 in CEU and GBI

c

Based on alpha of 0.05, case prevalence of 0.00714 (WNND in 1/140 of exposed), the respective odds ratios, risk allele frequencies, and sample population numbers for each variant.