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. Author manuscript; available in PMC: 2017 Jan 6.

Published in final edited form as: Biochem Cell Biol. 2015 Sep 15;93(6):604–610. doi: 10.1139/bcb-2015-0007

Fig. 1 — Impact of DFF40 expression and doxorubicin treatments on cell viability. Cell viability was assessed by the MTT assay and was calculated as percentage value relative to the blank (untreated) group. Concurrent treatment of doxorubicin (0.17, 0.22, and 0.33 μmol/L) with pIRES2 empty vector and pIRES2-DFF40 transfected cells (A: 24 h; B: 48 h; C: 72 h treatment) showed that DFF40-transfected cells exhibit a significant decrease in cell viability compared to the empty vector transfected cells, illustrating the augmented cytotoxicity of doxorubicin in its individual state. Data are shown as mean ± SD from 3 independent experiments. *P < 0.05 and **P < 0.001 indicate statistically significant difference between two columns, illustrated using the column linking “ ” symbol.

Inline graphic — Impact of DFF40 expression and doxorubicin treatments on cell viability. Cell viability was assessed by the MTT assay and was calculated as percentage value relative to the blank (untreated) group. Concurrent treatment of doxorubicin (0.17, 0.22, and 0.33 μmol/L) with pIRES2 empty vector and pIRES2-DFF40 transfected cells (A: 24 h; B: 48 h; C: 72 h treatment) showed that DFF40-transfected cells exhibit a significant decrease in cell viability compared to the empty vector transfected cells, illustrating the augmented cytotoxicity of doxorubicin in its individual state. Data are shown as mean ± SD from 3 independent experiments. *P < 0.05 and **P < 0.001 indicate statistically significant difference between two columns, illustrated using the column linking “ ” symbol.