Table 1.
Efficacy comparisons between preserved latanoprost and PF tafluprost
| Time/IOP parameter | Latanoprost (mmHg) | Tafluprost (mmHg) | P value |
|---|---|---|---|
| 06:00 | 22.5 ± 3.8 | 21.9 ± 3.7 | <0.001* |
| 10:00 | 22.8 ± 3.0 | 22.7 ± 3.6 | 1.0* |
| 14:00 | 21.5 ± 2.6 | 21.9 ± 3.0 | 0.468* |
| 18:00 | 22.5 ± 3.2 | 22.2 ± 3.4 | 1.0* |
| 22:00 | 22.2 ± 3.9 | 21.7 ± 3.8 | 0.126* |
| 02:00 | 21.6 ± 3.2 | 21.1 ± 3.5 | 0.027* |
| Mean 24-h IOP | 22.2 ± 2.9 | 21.9 ± 3.2 | 0.006 |
| Trough 24-h IOP | 19.9 ± 2.7 | 20.1 ± 2.8 | 0.421 |
| Peak 24-h IOP | 24.5 ± 3.3 | 23.9 ± 3.5 | 0.001 |
| 24-h fluctuation | 4.6 ± 1.6 | 3.9 ± 1.3 | 0.001 |
Results are presented as mean ± standard deviation
* Bonferroni-adjusted P values