Table 4.
Impact of distress from symptoms on health-related quality of life
| Symptom causing quite a lot of distress/very much distress | PROMIS total raw score | PROMIS physical health T-score | PROMIS mental health T-score | EuroQol 5D score | ||||
|---|---|---|---|---|---|---|---|---|
|
|
|
|
|
|||||
| Mean ± SD | Rank | Mean ± SD | Rank | Mean ± SD | Rank | Mean ± SD | Rank | |
| Vomiting | 21.37 ± 7.06 | 1 | 30.58 ± 7.41 | 1 | 35.21 ± 9.37 | 1 | 0.50 ± 0.10 | 1 |
| Dizziness | 22.97 ± 6.58 | 2 | 33.02 ± 7.16 | 3 | 37.13 ± 9.06 | 2 | 0.52 ± 0.52 | 2 |
| Nausea | 23.07 ± 6.59 | 3 | 32.70 ± 6.92 | 2 | 37.27 ± 8.79 | 3 | 0.52 ± 0.09 | 3 |
| Drowsiness | 23.55 ± 6.57 | 4 | 33.58 ± 6.81 | 6 | 37.79 ± 8.75 | 5 | 0.54 ± 0.10 | 7 |
| Shortness of breath | 23.55 ± 6.05 | 5 | 33.40 ± 6.20 | 4 | 38.62 ± 8.32 | 9 | 0.53 ± 0.08 | 4 |
| Lack of appetite | 23.68 ± 6.81 | 6 | 33.96 ± 7.24 | 9 | 37.93 ± 9.10 | 6 | 0.54 ± 0.10 | 8 |
| Change of taste | 23.79 ± 6.94 | 7 | 33.75 ± 8.12 | 7 | 38.05 ± 8.97 | 7 | 0.54 ± 0.10 | 5 |
| Lack of energy | 23.87 ± 6.09 | 8 | 33.56 ± 6.23 | 5 | 38.66 ± 8.31 | 10 | 0.54 ± 0.09 | 6 |
| Diarrhea | 24.48 ± 7.02 | 9 | 34.73 ± 7.26 | 12 | 37.78 ± 9.15 | 4 | 0.55 ± 0.11 | 12 |
| Bloating | 24.50 ± 6.32 | 10 | 34.30 ± 7.22 | 11 | 38.57 ± 8.08 | 8 | 0.55 ± 0.10 | 11 |
| Dry mouth | 24.61 ± 6.27 | 11 | 34.29 ± 6.64 | 10 | 38.88 ± 8.06 | 11 | 0.55 ± 0.09 | 10 |
| Itch | 24.91 ± 6.62 | 12 | 35.16 ± 7.44 | 15 | 39.51 ± 8.70 | 13 | 0.56 ± 0.10 | 13 |
| Pain | 24.97 ± 6.20 | 13 | 33.86 ± 5.82 | 8 | 40.50 ± 8.68 | 16 | 0.54 ± 0.08 | 9 |
| Constipation | 25.05 ± 6.28 | 14 | 35.05 ± 6.84 | 14 | 39.36 ± 7.98 | 12 | 0.56 ± 0.09 | 15 |
| Sexual dysfunction | 25.11 ± 7.25 | 15 | 35.03 ± 7.72 | 13 | 39.68 ± 8.81 | 14 | 0.56 ± 0.10 | 14 |
| Cough | 25.86 ± 6.49 | 16 | 35.89 ± 7.46 | 16 | 40.19 ± 8.50 | 15 | 0.57 ± 0.10 | 16 |
| Weight loss | 27.97 ± 6.02 | 17 | 37.66 ± 7.02 | 17 | 42.40 ± 7.78 | 17 | 0.59 ± 0.09 | 17 |
PROMIS Patient-Reported Outcomes Measurement Information System, SD standard deviation