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. Author manuscript; available in PMC: 2017 Sep 1.
Published in final edited form as: Pediatr Allergy Immunol. 2016 May 27;27(6):604–611. doi: 10.1111/pai.12580

Table 3.

Association between allergic disease, adequate nights of sleep per week, and speech disorder in NSCH 2003/4 and 2007/8

History of speech disorder
No (n = 128,075) Yes (n = 3555)
Nights of adequate sleep per week Freq Freq % Prevalence Crude OR (95% CI) p-value Adjusted OR (95% CI) p-value
Current asthma
 No 4–7 105,686 2632 2.7 (2.5–2.9) 1.00 1.00
 No 0–3 9652 296 3.9 (3.0–4.8) 1.50 (1.16–1.94) 0.002 1.76 (1.32–2.34) 0.0001
 Yes 4–7 11,025 541 6.1 (5.0–7.2) 2.38 (1.93–2.92) <0.0001 1.56 (1.22–1.983) 0.0003
 Yes 0–3 2049 112 7.8 (4.4–11.2) 3.10 (1.92–5.01) <0.0001 2.51 (1.64–3.88) <0.0001
Hay fever
 No 4–7 95,000 2275 2.7 (2.5–2.9) 1.00 1.00
 No 0–3 8492 243 4.0 (2.9–5.1) 1.52 (1.13–2.04) 0.005 1.81 (1.33–2.48) 0.0002
 Yes 4–7 21,862 902 4.4 (3.9–4.9) 1.67 (1.43–1.94) <0.0001 1.29 (1.09–1.53) 0.003
 Yes 0–3 2579 135 6.0 (4.3–7.7) 2.32 (1.70–3.18) <0.0001 2.06 (1.46–2.91) <0.0001
Food allergy
 No 4–7 112,700 2881 2.8 (2.6–3.0) 1.00 1.00
 No 0–3 10,541 328 4.1 (3.1–5.0) 1.50 (1.16–1.92) 0.002 1.76 (1.35–2.29) <0.0001
 Yes 4–7 4280 296 9.3 (6.9–11.6) 3.60 (2.69–4.81) <0.0001 2.35 (1.61–3.43) <0.0001
 Yes 0–3 545 49 12.1 (6.7–17.6) 4.88 (2.92–8.14) <0.0001 3.80 (2.13–6.79) <0.0001

Binary logistic regression models were constructed with history of speech disorder as the dependent variable and the interaction between current asthma, hay fever, or food allergy and nights of adequate sleep per week (0–3/4–7) as the independent variable. Multivariate models were also constructed that additionally included history of eczema, sex, age, race, household income, highest level of household education, US vs. foreign birthplace, insurance coverage, and outpatient healthcare utilization in the past year (all categorical) as independent variables. Adjusted prevalence odds ratios and 95% confidence intervals were estimated. Bold values indicate P < 0.05.