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. Author manuscript; available in PMC: 2017 Nov 1.
Published in final edited form as: Br J Dermatol. 2016 Aug 28;175(5):920–929. doi: 10.1111/bjd.14697

Table 5.

Association between allergic disease, anaemia, adiposity and ADD/ADHD in children with eczema (n = 35 865)

Variable ADD/ADHD
No (n = 32 504) Yes (n = 3361)
Freq Freq % Prev (95% CI) Crude OR (95% CI) Adjusted OR (95% CI)
Anaemia
 No 15 291 1505 9·0 (8·5–9·4) 1·00 (ref) 1·00 (ref)
 Yes 384 68 15·0 (11·7–18·3) 1·80 (1·382·34) 1·84 (1·372·46)
Headaches
 No 24 893 2646 9·6 (9·3–10·0) 1·00 (ref) 1·00 (ref)
 Yes 2656 626 19·0 (17·7–20·4) 2·22 (2·022·44) 1·66 (1·491·85)
Body mass index (percentile)
 < 5 356 77 17·8 (14·2–21·4) 1·38 (1·071·78) 1·20 (0·87–1·64)
 5–84 5591 878 13·6 (12·7–14·4) 1·00 (ref) 1·00 (ref)
 85–94 1560 277 15·1 (13·4–16·7) 1·13 (0·98–1·31) 1·10 (0·92–1·30)
 ≥ 95 1485 366 19·8 (18·0–21·6) 1·57 (1·371·80) 1·28 (1·081·50)

Binary, unweighted logistic regression models were constructed with ADD/ADHD as the dependent variable and history of allergic disease, anaemia and body mass index for age and sex percentiles as the independent variables. Analyses were limited to subjects with a history of eczema. Multivariate logistic regression models were then constructed that included sex, age, race, household income, highest level of household education, U.S. vs. foreign birthplace and insurance coverage as the independent variables. Crude and adjusted prevalence ORs and 95% CIs were estimated. ADD/ADHD, attention deficit (hyperactivity) disorder; CI, confidence interval; freq, frequency; OR, odds ratio; prev, prevalence; bold indicates significance.