Table 6.

Association between allergic disease, headaches, insomnia, adiposity and attention deficit (hyperactivity) disorder (ADD/ADHD) in adults with eczema (n = 2488)

Variable	ADD/ADHD
	No (n = 32 504)	Yes (n = 173)
	Freq	Freq	% Prev (95% CI)	Crude OR (95% CI)	Adjusted OR (95% CI)
Ever asthma
No	1756	96	5·3 (4·0–6·7)	1·00 (ref)	1·00 (ref)
Yes	552	77	13·8 (9·1–18·5)	2·83 (1·76–4·55)	2·63 (1·58–4·37)
Hay fever
No	1986	141	7·2 (5·5–8·9)	1·00 (ref)	1·00 (ref)
Yes	322	32	9·3 (5·2–13·3)	1·32 (0·76–2·28)	1·57 (0·88–2·81)
Food allergy
No	2000	133	6·3 (4·9–7·6)	1·00 (ref)	1·00 (ref)
Yes	305	40	15·6 (7·8–23·3)	2·77 (1·47–5·20)	3·07 (1·64–5·77)
Headaches
No	1738	107	6·0 (4·5–7·4)	1·00 (ref)	1·00 (ref)
Yes	571	66	12·0 (7·5–16·4)	2·14 (1·30–3·52)	2·10 (1·17–3·75)
Insomnia
No	1497	80	5·7 (3·7–7·7)	1·00 (ref)	1·00 (ref)
Yes	813	93	10·9 (8·2–13·5)	2·01 (1·27–3·19)	2·18 (1·28–3·71)
Number of allergic disorders
0	1423	64	4·6 (3·2–6·0)	1·00 (ref)	1·00 (ref)
1	627	74	9·7 (6·9–12·4)	2·22 (1·42–3·58)	2·29 (1·43–3·66)
2 or more	251	35	17·8 (8·8–26·8)	4·49 (2·25–8·96)	4·91 (2·43–9·93)
Body mass index class
Underweight	45	4	2·4 (0·0–4·9)	0·32 (0·10–1·01)	0·18 (0·03–0·96)
Normal weight	754	60	7·1 (4·9–9·2)	1·00 (ref)	1·00 (ref)
Overweight	696	47	6·7 (4·2–9·3)	0·95 (0·56–1·61)	1·06 (0·62–1·81)
Obese	723	58	9·6 (5·9–13·4)	1·40 (0·81–2·41)	1·66 (0·96–2·87)

Binary, weighted logistic regression models were constructed with ADD/ADHD as the dependent variable and history of allergic disease, headaches, insomnia and body mass index class as the independent variables. Analyses were limited to subjects with a history of eczema. Multivariate logistic regression models were then constructed that included sex, age, race, household income, highest level of household education, U.S. vs. foreign birthplace and insurance coverage as the independent variables. Crude and adjusted prevalence ORs and 95% CIs were estimated. CI, confidence interval; freq, frequency; OR, odds ratio; prev, prevalence; bold indicates significance.