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Risk of major or CRNM bleeding for dabigatran, rivaroxaban, and apixaban compared with warfarin in the subgroup of patients ≥75 years. Crude IR for first bleeding episode are given as events per 100 person-years. CI, confidence interval; CRNM, clinically relevant non-major bleeding; HR, adjusted hazard ratio; IR, incidence rate; OAC, oral anticoagulant.
