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. 2017 Jan 5;24(1):e00370-16. doi: 10.1128/CVI.00370-16

TABLE 1.

Serum from PCR-positive cases 4 to 9 weeks after symptom onseta

Sample Sex/age (yr)b CT value Primary vaccine series aP boost Date (mo/day/yr) of:
Time from symptom onset to sample (wk) ACT ELISA (U/ml) TNA (%)d PT ELISA (U/ml)
Last vaccination Approx symptom onsetc
V002 F/14 26.3 5 aP + 03/14/11 08/25/14 8 47.3 100 300
V003 M/17 HCe 5 aP + 08/14/08 08/11/14 4 44.8 100 640
V006 F/18 28.1 5 ap + 07/08/08 05/15/15 6 4.8 0 24.1
V007 M/16 14.0 5 aP + 07/20/10 05/28/15 4 63.9 100 464
V008 F/17 27.8 5 aP + 08/08/11 05/28/15 5 30.5 85.4 184
V009 M/12 20.6 5 aP 08/06/08 05/05/15 8 93.7 100 215
V010 M/13 23.2 5 aP + 10/14/12 06/01/15 5 156 100 73.8
V011 M/22 34.5 3 wP, 2 aP + 04/27/07 07/26/15 4 30.6 95.5 413
V012 M/15 29.0 5 aP + 08/30/10 05/07/15 9 45.5 85.4 803
V013 F/18 19.5 5 ap + 07/10/08 06/17/15 9 23.6 69.8 329
V014 M/13 32.9 5 aP + 08/23/13 07/01/15 7 9.8 19.3 94.1
V015 F/15 32.7 5 aP + 08/07/12 09/21/15 5 21.7 60.4 276
V016 F/14 36.2 5 aP + 01/18/12 09/20/15 6 54.3 97.4 170
V017 F/15 17.5 5 aP + 01/14/11 10/23/15 6 44.4 98.0 290
V018 M/15 31.9 5 aP + 06/28/11 10/22/15 7 0.71 0 1,404
V019 F/17 29.8 5 aP + 08/18/09 11/01/15 5 30.0 81.1 563
V020 M/17 27.5 5 aP + 04/23/10 11/14/15 4 3.28 0 293
V021 M/14 32.1 5 aP + 02/13/13 10/12/15 7 0.75 0 1,040
a

Bolded values are considered positive (see Table 2 for data from normal controls). Data represent the mean of the results from each sample tested in duplicate (ELISA) or triplicate (TNA).

b

F, female; M, male.

c

At onset of clinical illness, all subjects reported symptoms consistent with pertussis.

d

Percent toxin neutralization using a 1:50 final serum dilution, as described in Materials and Methods.

e

HC, sample was from a household contact of subject V002 with clinical symptoms of pertussis.