TABLE 1.
Sample | Sex/age (yr)b | CT value | Primary vaccine series | aP boost | Date (mo/day/yr) of: |
Time from symptom onset to sample (wk) | ACT ELISA (U/ml) | TNA (%)d | PT ELISA (U/ml) | |
---|---|---|---|---|---|---|---|---|---|---|
Last vaccination | Approx symptom onsetc | |||||||||
V002 | F/14 | 26.3 | 5 aP | + | 03/14/11 | 08/25/14 | 8 | 47.3 | 100 | 300 |
V003 | M/17 | HCe | 5 aP | + | 08/14/08 | 08/11/14 | 4 | 44.8 | 100 | 640 |
V006 | F/18 | 28.1 | 5 ap | + | 07/08/08 | 05/15/15 | 6 | 4.8 | 0 | 24.1 |
V007 | M/16 | 14.0 | 5 aP | + | 07/20/10 | 05/28/15 | 4 | 63.9 | 100 | 464 |
V008 | F/17 | 27.8 | 5 aP | + | 08/08/11 | 05/28/15 | 5 | 30.5 | 85.4 | 184 |
V009 | M/12 | 20.6 | 5 aP | 08/06/08 | 05/05/15 | 8 | 93.7 | 100 | 215 | |
V010 | M/13 | 23.2 | 5 aP | + | 10/14/12 | 06/01/15 | 5 | 156 | 100 | 73.8 |
V011 | M/22 | 34.5 | 3 wP, 2 aP | + | 04/27/07 | 07/26/15 | 4 | 30.6 | 95.5 | 413 |
V012 | M/15 | 29.0 | 5 aP | + | 08/30/10 | 05/07/15 | 9 | 45.5 | 85.4 | 803 |
V013 | F/18 | 19.5 | 5 ap | + | 07/10/08 | 06/17/15 | 9 | 23.6 | 69.8 | 329 |
V014 | M/13 | 32.9 | 5 aP | + | 08/23/13 | 07/01/15 | 7 | 9.8 | 19.3 | 94.1 |
V015 | F/15 | 32.7 | 5 aP | + | 08/07/12 | 09/21/15 | 5 | 21.7 | 60.4 | 276 |
V016 | F/14 | 36.2 | 5 aP | + | 01/18/12 | 09/20/15 | 6 | 54.3 | 97.4 | 170 |
V017 | F/15 | 17.5 | 5 aP | + | 01/14/11 | 10/23/15 | 6 | 44.4 | 98.0 | 290 |
V018 | M/15 | 31.9 | 5 aP | + | 06/28/11 | 10/22/15 | 7 | 0.71 | 0 | 1,404 |
V019 | F/17 | 29.8 | 5 aP | + | 08/18/09 | 11/01/15 | 5 | 30.0 | 81.1 | 563 |
V020 | M/17 | 27.5 | 5 aP | + | 04/23/10 | 11/14/15 | 4 | 3.28 | 0 | 293 |
V021 | M/14 | 32.1 | 5 aP | + | 02/13/13 | 10/12/15 | 7 | 0.75 | 0 | 1,040 |
Bolded values are considered positive (see Table 2 for data from normal controls). Data represent the mean of the results from each sample tested in duplicate (ELISA) or triplicate (TNA).
F, female; M, male.
At onset of clinical illness, all subjects reported symptoms consistent with pertussis.
Percent toxin neutralization using a 1:50 final serum dilution, as described in Materials and Methods.
HC, sample was from a household contact of subject V002 with clinical symptoms of pertussis.