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CtxB-specific IgG response for vaccine and placebo recipients before and after cholera challenge. Mean fold change of anti-CtxB IgG antibodies for placebo and vaccine recipients challenged at day 10 (A) and day 90 (B). To the left of the dashed line are days before cholera challenge, and to the right are days following challenge. Error bars represent standard errors of the means, and an asterisk denotes differences between placebo and vaccine recipients with a P value of <0.05.
