Table 2.

Evenness index of lung pieces at 5 minutes post-dosing from the apex to the base of rat lungs dosed with ¹⁴¹CeO₂ nanoparticles using different techniques.

Apex-to-base section	IT Instillation	Microspray	Left Intrabronchial	Insufflation
	Mean ± SE	Mean ± SE	Mean ± SE	Mean ± SE
A	0.38 ± 0.06	0.90 ± 0.21	0.17 ± 0.09	0.20 ± 0.13
B	0.92 ± 0.17	1.26 ± 0.12	1.21 ± 0.50	0.51 ± 0.26
C	1.22 ± 0.23	1.58 ± 0.23	0.89 ± 0.30	0.24 ± 0.10
D	0.84 ± 0.05	1.00 ± 0.12	1.15 ± 0.30	0.49 ± 0.09
E	1.09 ± 0.07	1.36 ± 0.14	1.82 ± 0.28	0.78 ± 0.36
F	1.04 ± 0.07	1.31 ± 0.09	2.84 ± 0.54	0.68 ± 0.11
G	1.44 ± 0.11	1.47 ± 0.07	2.05 ± 0.41	0.69 ± 0.13
H	1.37 ± 0.21	1.55 ± 0.15	1.69 ± 0.47	0.87 ± 0.18
I	1.14 ± 0.15	1.22 ± 0.12	1.75 ± 0.33	1.47 ± 0.49
J	0.77 ± 0.18	0.81 ± 0.15	1.75± 0.19	1.43 ± 0.45
All sections	1.02 ± 0.10	1.25 ± 0.08	1.41 ± 0.24	0.74 ± 0.14
Coefficient of variation	31%	22%	55%	59%

Data are mean ± SE of EI in each apex-to-base section, n=6 rats/group. Evenness indices in the left intrabronchial group were based on lung slices in the left lung lobe only.