Table 5.

Adjusted odds ratios (AORs) and 95% confidence intervals (CIs) with supporting mediation effect showing the increase in odds for suicidal ideation and depressive ideas at 45 years, for each childhood adversity ^a

	In the past week have you felt that life isn't worth living?			Depressive ideas
Adversity	AOR (95% CI)	Indirect percentage of total mediation effect		AOR (95% CI)	Indirect percentage of total mediation effect
		Life events	Number of partnerships in adulthood		Life events	Number of partnerships in adulthood
		Mean % (95% CI)	Mean % (95% CI)		Mean % (95% CI)	Mean % (95% CI)
Illness in the household	2.00 (1.41–2.83)***	1.55 (1.01–2.78)	−0.50 (−1.11 to −0.17)	1.24 (1.00–1.55)	5.59 (−1.15 to 24.44)	−0.88 (−6.14 to 2.95)
Neglected/underfed appearance at 7–11 years	1.36 (0.73–2.54)			1.25 (0.83–1.88)
Maternal absence	0.85 (0.45–1.63)			0.90 (0.63–1.28)
Paternal absence	1.92 (1.34–2.75)***	2.49 (1.45–5.62)	1.27 (0.76–2.91)	1.19 (0.95–1.49)
In care	1.74 (0.98–3.11)			1.28 (0.87–1.89)
Divorce of parents by age 16 years b	1.58 (1.07–2.35)*	6.34 (−7.16 to 36.75)	2.27 (−3.72 to 14.19)	1.14 (0.89–1.46)
Parental physical abuse c	2.25 (1.49–3.41)***	9.59 (4.97–27.88)	5.22 (2.65–16.38)	2.13 (1.66–2.74)***	11.79 (8.14–19.09)	2.97 (2.01–5.02)
Parental sexual abuse c	2.64 (1.42–4.93)**	6.59 (2.40–38.36)	4.71 (0.93–28.69)	2.32 (1.53–3.53)***	8.16 (4.72–18.53)	2.73 (1.57–6.50)
Cumulative adversity scale
1	1.67 (1.03–2.70)*			1.30 (1.00–1.69)*
2	2.21 (1.31–3.74)**			1.34 (1.00–1.80)
3 or more	3.25 (1.97–5.37)***			1.68 (1.27–2.24)***

^aAdjusted for gender, social class at 42 years, qualifications at 33 years, life events at 45 years, number of partnerships in adulthood, number of periods of unemployment in adulthood, emotional support at 42 years, problem drinking at 33 or 42 years, long-standing illness at 42 years and psychological distress at 16 years (any internalizing or externalizing at 16 years).

^bReported at 33 years.

^cReported at 45 years.

* p ⩽ 0.05, ** p ⩽ 0.01, *** p ⩽ 0.001.