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. 2004 Sep 23;32(17):5003–5010. doi: 10.1093/nar/gkh831

Table 2. Rates of spontaneous CanR and Lys+ mutations in ogg1, rad6 and rad18 mutants of S.cerevisiae.

Genotype CanR mutation rate (10−7) Lys+ mutation rate (10−8)
Wild-type 3.6 ± 1.4 [1] 3.8 ± 2.2 [1]
Δ ogg1 18.0 ± 3.1 [5] 33.3 ± 6.0 [9]
Δ rad6 7.6 ± 1.4 [2] 4.2 ± 1.2 [1]
Δ rad18 12.9 ± 1.9 [4] 9.7 ± 2.3 [3]
Δ ogg1 Δ rad6 126.3 ± 11.5 [35] 85.6 ± 13.6 [23]
Δ ogg1 Δ rad18 109.4 ± 11.1 [30] 126.6 ± 19.8 [33]
Δ ogg1 Δ rad6 Δ rad18 105.6 ± 14.9 [29] ND

CanR and Lys+ mutation rates were determined using the method of the median (50). Numbers in brackets are the fold induction relative to the wild-type value. ND, not determined.