Table 5. Rates of spontaneous CanR mutations in ogg1, rad18 and msh6 mutants of S.cerevisiae.
Genotype | CanR mutation rate (10−7) |
---|---|
Wild-type | 3.6 ± 1.4 [1] |
Δ ogg1 | 18.0 ± 3.1 [5] |
Δ msh6 | 20.7 ± 2.6 [6] |
Δ rad18 | 12.9 ± 1.9 [4] |
Δ ogg1 Δ msh6 | 161.8 ± 20.9 [45] |
Δ ogg1 Δ rad18 | 109.4 ± 11.1 [30] |
Δ ogg1 Δ rad18 Δ msh6 | 171.1 ± 22.1 [48] |
The mutation rates are determined as described in Table 2. Numbers in brackets are the fold induction relative to the wild-type values. ND, not determined.