Table 2.
Age and gender standardized rates of AMI among Korean adults according to the presence or absence of diabetes (2006–2013)
| Variables | Year | Change | P value | ||||
|---|---|---|---|---|---|---|---|
| 2006–2007 | 2008–2009 | 2010–2011 | 2012–2013 | Absolute change | Percent change | Linear trend | |
| AMI | |||||||
| Overall population | |||||||
| No. of events/10,000 in diabetes | 87.09 | 81.36 | 61.67 | 54.62 | −32.47 | −37.28 | <.0001 |
| 95% CI | 85.27–88.91 | 79.82–82.89 | 60.64–62.69 | 53.71–55.54 | |||
| No. of events/10,000 in non-diabetes | 26.31 | 26.15 | 21.43 | 19.59 | −17.21 | −25.50 | <.0001 |
| 95% CI | 26.29–26.33 | 26.13–26.17 | 21.42–21.45 | 19.57–19.60 | |||
| RR (95% CI) | 3.31 (3.24–3.38) | 3.11 (3.05–3.18) | 2.88 (2.82–2.94) | 2.79 (2.73–2.85) | <.0001 | ||
| Men | |||||||
| No. of events/10,000 in diabetes | 100.97 | 92.90 | 73.55 | 66.12 | −34.85 | −34.52 | <.0001 |
| 95% CI | 97.37–104.58 | 89.84–95.95 | 71.34–75.77 | 64.16–68.08 | |||
| No. of events/10,000 in non-diabetes | 30.34 | 29.51 | 24.13 | 22.27 | −8.07 | −26.60 | <.0001 |
| 95% CI | 30.29–30.39 | 29.46–29.56 | 24.09–24.16 | 22.24–22.30 | |||
| RR (95% CI) | 3.33 (3.26–3.4) | 3.15 (3.08–3.21) | 3.05 (2.98–3.11) | 2.97 (2.91–3.03) | <.0001 | ||
| Women | |||||||
| No. of events/10,000 in diabetes | 74.17 | 70.61 | 50.60 | 43.92 | −30.25 | −40.78 | <.0001 |
| 95% CI | 70.52–77.81 | 67.52–73.69 | 48.69–52.51 | 42.21–45.62 | |||
| No. of events/10,000 in non-diabetes | 22.55 | 23.01 | 18.92 | 17.09 | −5.46 | −24.21 | <.0001 |
| 95% CI | 22.52–22.59 | 22.98–23.05 | 18.89–18.95 | 17.07–17.11 | |||
| RR (95% CI) | 3.29 (3.21–3.37) | 3.07 (3.00–3.14) | 2.67 (2.61–2.74) | 2.57 (2.51–2.63) | <.0001 | ||
| Aged < 65 years | |||||||
| No. of events/10,000 in diabetes | 66.35 | 63.53 | 47.05 | 42.57 | −23.78 | −35.84 | <.0001 |
| 95% CI | 63.62–69.08 | 61.09–65.98 | 45.57–48.52 | 41.20–43.93 | |||
| No. of events/10,000 in non-diabetes | 14.12 | 14.25 | 11.63 | 10.70 | −3.42 | −24.22 | <.0001 |
| 95% CI | 14.11–14.13 | 14.24–14.27 | 11.62–11.64 | 10.69–10.71 | |||
| RR (95% CI) | 4.70 (4.59–4.81) | 4.46 (4.36–4.56) | 4.05 (3.95–4.15) | 3.98 (3.88–4.08) | <.0001 | ||
| Aged ≥ 65 years | |||||||
| No. of events/10,000 in diabetes | 202.04 | 186.77 | 145.69 | 122.44 | −79.60 | −39.40 | <.0001 |
| 95% CI | 185.21–218.87 | 175.20–198.33 | 138.61–152.77 | 118.07–126.81 | |||
| No. of events/10,000 in non-diabetes | 100.86 | 101.48 | 84.69 | 75.72 | −25.14 | −24.93 | <.0001 |
| 95% CI | 99.83–101.88 | 100.54–102.41 | 83.98–85.41 | 75.17–76.28 | |||
| RR (95% CI) | 2.00 (1.96–2.05) | 1.84 (1.8–1.88) | 1.72 (1.68–1.76) | 1.62 (1.58–1.65) | <.0001 | ||
In the whole analysis, P values for interaction between diabetes status and years was less than .0001 by regression models