Table 4.
Age and gender standardized rates hemorrhagic stroke among Korean adults according to the presence or absence of diabetes (2006–2013)
| Variables | Year | Change | P value | ||||
|---|---|---|---|---|---|---|---|
| 2006–2007 | 2008–2009 | 2010–2011 | 2012–2013 | Absolute change | Percent change | Linear trend | |
| Hemorrhagic stroke | |||||||
| Overall population | |||||||
| No. of events/10,000 in diabetes | 66.44 | 61.22 | 54.65 | 46.43 | −20.01 | −30.12 | <.0001 |
| 95% CI | 65.09–67.8 | 60– 62.45 | 53.57–55.72 | 45.5–47.36 | |||
| No. of events/10,000 in non-diabetes | 35.94 | 32.85 | 29.23 | 25.35 | −10.59 | −29.47 | <.0001 |
| 95% CI | 35.91–35.97 | 32.83–32.88 | 29.21–29.25 | 25.33–25.37 | |||
| RR (95% CI) | 1.85 (1.80–1.89) | 1.86 (1.82–1.91) | 1.87 (1.83–1.91) | 1.83 (1.79–1.87) | <.0001 | ||
| Men | |||||||
| No. of events/10,000 in diabetes | 69.60 | 64.00 | 58.65 | 47.92 | −21.68 | −31.15 | <.0001 |
| 95% CI | 67.48–71.73 | 62.04–65.96 | 56.96–60.33 | 46.57–49.27 | |||
| No. of events/10,000 in non-diabetes | 37.65 | 34.6 | 31.14 | 26.83 | −10.82 | −28.74 | <.0001 |
| 95% CI | 37.59–37.72 | 34.55–34.66 | 31.10–31.19 | 26.8 –26.87 | |||
| RR (95% CI) | 1.85 (1.8–1.89) | 1.85 (1.81–1.89) | 1.88 (1.84–1.93) | 1.79 (1.75–1.83) | <.0001 | ||
| Women | |||||||
| No. of events/10,000 in diabetes | 63.5 | 58.64 | 50.93 | 45.04 | −18.46 | −29.07 | <.0001 |
| 95% CI | 60.28–66.71 | 55.78–61.51 | 48.38–53.47 | 42.73–47.35 | |||
| No. of events/10,000 in non-diabetes | 34.35 | 31.22 | 27.45 | 23.97 | −10.38 | −30.22 | <.0001 |
| 95% CI | 34.30–34.41 | 31.18–31.27 | 27.41–27.49 | 23.94–24.00 | |||
| RR (95% CI) | 1.85 (1.80–1.90) | 1.88 (1.83–1.93) | 1.86 (1.81–1.90) | 1.88 (1.83–1.93) | <.0001 | ||
| Aged < 65 years | |||||||
| No. of events/10,000 in diabetes | 51.91 | 48.43 | 42.66 | 37.41 | −14.5 | −27.93 | <.0001 |
| 95% CI | 50.05–53.78 | 46.69–50.17 | 41.10–44.22 | 35.96–38.86 | |||
| No. of events/10,000 in non-diabetes | 23.34 | 20.79 | 18.48 | 16.18 | −7.16 | −30.68 | <.0001 |
| 95% CI | 23.32–23.36 | 20.77–20.81 | 18.46–18.49 | 16.16–16.19 | |||
| RR (95% CI) | 2.22 (2.17–2.28) | 2.33 (2.27–2.39) | 2.31 (2.25–2.37) | 2.31 (2.25–2.37) | <.0001 | ||
| Aged ≥ 65 years | |||||||
| No. of events/10,000 in diabetes | 145.8 | 132.03 | 122.85 | 101.88 | −43.92 | −30.12 | <.0001 |
| 95% CI | 133.07–158.54 | 123.83–140.22 | 116.69–129.00 | 98.04–105.72 | |||
| No. of events/10,000 in non-diabetes | 106.26 | 103.24 | 94.47 | 82.17 | −24.09 | −22.67 | <.0001 |
| 95% CI | 105.23–107.29 | 102.33–104.15 | 93.7–95.24 | 81.58–82.77 | |||
| RR (95% CI) | 1.37 (1.34–1.41) | 1.28 (1.25–1.31) | 1.3 (1.27–1.33) | 1.24 (1.21–1.27) | <.0001 | ||
In the whole analysis, P values for interaction between diabetes status and years was less than .0001 by regression models