Fig. 1.

Identification of lncRNAs that were differently expressed as expected based on the lncRNA and mRNA microarray results. a Ovalbumin (OVA)-induced allergy was established both in vivo and in vitro. b Long noncoding RNAs (lncRNAs) and mRNAs that were differentially expressed in vivo and in vitro were isolated from the microarray data. c Twenty-three lncRNAs and 96 mRNAs expressed in the same manner (up or down after the induction of asthma and down or up with the treatment of induced pluripotent stem cell-mesenchymal stem cells (iPSC-MSCs)), both in vivo and in vitro, were selected. d Target prediction of the 23 lncRNAs was carried out; Pearson’s correlation coefficient with mRNAs involved in allergy was utilized to screen out 9 of the 23 lncRNAs. Gene ontology and pathway analysis of the co-expressed mRNAs was carried out to investigate the correlated functions of the genes. PBS phosphate-buffered saline, Tm memory T