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. 2017 Jan 6;8:2. doi: 10.1186/s13287-016-0456-3

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — iPSC-MSCs alleviated airway allergy in vivo and reduced Th2 cytokines dramatically in vitro. a Representative photomicrographs of hematoxylin and eosin (HE)- and periodic acid-Schiff (PAS)-stained lung sections. Original magnification 200×. b The inflammatory infiltration and goblet cell hyperplasia was quantified by HE and PAS scores (n = 6). c Th2 cytokines IL-4 and IL-13 were detected in the supernatant. Memory T (Tm) cells were separated from the spleens of the mice and cultured in vitro (n = 5). **p < 0.01. PBS phosphate-buffered saline, IL interleukin, iPSC-MSC induced pluripotent stem cell-mesenchymal stem cell, OVA ovalbumin