Fig. 3.

Methylation status of the MEG3 promoter in cervival cancer. a Methylation status of MEG3 promoter in cervival cancer tissues (C1-C5 as example) and its corresponding normal tissues (N1-N5 as example) was tested by MSP. The methylated pattern (M) of MEG3 was 160 bp and the unmethylated pattern (U) was 120 bp. b Patients were classified into methylation group (M), partially methylated group (MU) and unmethylated group (U) based on the methylation levels of MEG3 promoter. MEG3 expression level was associated with the methylation level of MEG3 promoter. c Hypermethylation of MEG3 promoter indicated poor recurrence-free survival. ^* P < 0.05, ^** P < 0.01