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. 2017 Jan 5;36:5. doi: 10.1186/s13046-016-0472-2

Table 1.

Univariate and Multivariate analyses for recurrence-free survival

Risk factors Univariate analysis Multivariate analysis
HR P value 95% CI HR P value 95% CI
MEG3 expression 0.111 0.002 0.027 ∼ 0.451 0.159 0.040 0.028 ∼ 0.919
FIGO stage, (I, II) 3.687 <0.001 1.780 ∼ 7.634 3.033 0.005 1.400 ∼ 6.571
Lymph nodes metastasis (Negative, Positive) 2.095 0.043 1.023 ∼ 4.291 2.259 0.048 1.007 ∼ 5.070
Differentiation (Well/Moderately, Poorly) 2.134 0.040 1.036 ∼ 4.396 0.670 0.406 0.201 ∼ 1.722
Depth of invasion (≤2/3, >2/3) 1.358 0.403 0.663 ∼ 2.783
HR HPV infection (Negative, Positive) 1.501 0.347 0.643 ∼ 3.502
Tumor size 1.243 0.132 0.936 ∼ 1.652
LVSI (Negative, Positive) 0.797 0.538 0.387 ∼ 1.643
Age 0.998 0.894 0.967 ∼ 1.030
Histology (Squamous, Adenocarcinoma) 0.927 0.961 0.412 ∼ 2.240
Menopause (Yes, No) 1.426 0.333 0.696 ∼ 2.921

HR hazard ratio