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. 2017 Jan 5;13:4. doi: 10.1186/s12917-016-0917-z

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Effectiveness of regionally-specific immunotherapy in dogs versus change in lesion severity. The change in LSI equals the LSI at D270+ minus the LSI at D0. The line is a locally weighted scatterplot smoother with the shaded area showing the 95% confidence interval around the point-wise mean