Table 1.

Basic Membrane Properties of Q175 SPNs

	3 Months			9 Months
Property	WT (n =  9)	HET (n =  26)	HOM (n =  13)	WT (n =  10)	HET (n =  16)	HOM (n =  13)
Vm (mV)	76.5 ± 2.1	75.5 ± 1.4	74.8 ± 1.8	75.8 ± 2.4	74.8 ± 1.3	66.8 ± 2.6*,#
Rm (MΩ)	228.0 ± 69.4	198.9 ± 20.0	307.0 ± 38.6#	181.7 ± 36.3	192.7 ± 22.9	249.9 ± 34.7
Cm (pF)	104.8 ± 8.1	89.6 ± 4.8	86.7 ± 4.2	72.2 ± 5.0	73.8 ± 6.3	64.4 ± 8.8

Sample sizes in parentheses. Sample means ± S.E.M. are presented.

^*=different from WT P < 0.05.

^#=different from HET P < 0.05.