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. 2017 Jan 1;23(1):124–134. doi: 10.5056/jnm16042

Table 1.

Fermentation Conditions Used in the Environmental Control System for Intestinal Microbiota System to Simulation a Normal and a Slow Transit Time by a Modification of the Retention Time

Reactor pH Dilution rate (hr−1) Retention time (hr) Minimum doubling time (hr)
Simulation of a 48 hr transit
 P48 5.8 0.080 12.48 8.65
 T48 6.2 0.056 17.76 12.31
 D48 6.8 0.056 17.76 12.31
Simulation of an 96 hr transit
 P96 5.8 0.040 24.96 17.3
 T96 6.2 0.028 35.52 24.62
 D96 6.8 0.028 35.52 24.62

Minimum doubling time means the minimum doubling time of each bacterial species to avoid washing from the reactor and therefore the disappearance of the species when analyzed at steady-state.

P48, T48, and D48 indicate respectively the P (proximal), T (transversal), and D (distal) reactor simulating a 48-hour transit. P96, T96, and D96 indicate respectively the P (proximal), T (transversal), and D (distal) reactor simulating an 96-hour transit.