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. 2016 Feb 3;7(29):45005–45014. doi: 10.18632/oncotarget.7154

Figure 4. Functional annotation of pHH3 in TCGA GBM microarray data (N=603).

Figure 4

A. Gene Set Enrichment Analysis (GSEA) showed enrichment of EMT (epithelial to mesenchymal transition) related genes in patients classified by pHH3 signature. B. Biological processes enriched in pHH3 subtypes and representative enrichment plots. C. GSEA analysis of immune associated gene sets and representative enrichment plots. NES, normalized enrichment score; FDR, false discovery rate; NOM p value, nominal p value; MC, mesenchymal-classical subtype; PN, proneural-neural subtype; All the gene sets were downloaded from Molecular Signature Database (MSigDB) in GSEA website.