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. 2016 May 26;7(29):45331–45351. doi: 10.18632/oncotarget.9644

Figure 5. Aldo-induced autophagy is not mediated by inhibiting classic Akt-mTOR signaling in podocytes.

Figure 5

A. Western blot analysis revealed the expression of p-Akt, Akt, p-mTOR, mTOR, p-S6K1, S6K1, p-4EBP1, 4EBP1, and β-actin proteins after treatment with 10-7 M Aldo for various time periods, as indicated. B. Graphical presentation shows the relative abundance levels of p-Akt, p-mTOR, p-S6K1, and p-4EBP1 after normalization with Akt, mTOR, S6K1, 4EBP1, and β-actin, respectively. Results (means±SEM) of 3 series of experiments. #P<0.05 vs. normal control.