Table 1. Correlations between clinicopathological features and miR-138-5p expression in CRC.
| Feature | All | miR-138-5p level | ||
|---|---|---|---|---|
| Low (n) | High (n) | P-value | ||
| PD-L1 expression | ||||
| PD-L1 high | 98 | 73(74.5%) | 25(25.5%) | |
| PD-L1 low | 90 | 30(33.3%) | 60(66.7%) | 0.000* |
| age | ||||
| <55 | 87 | 47(54.0%) | 40(46.0%) | 0.884 |
| ≥55 | 101 | 56(55.4%) | 45(44.6%) | |
| sex | ||||
| Male | 120 | 67(55.8%) | 53(44.2%) | 0.702 |
| Female | 68 | 36(52.9%) | 32(47.1%) | |
| Differentiation | ||||
| Well | 61 | 34(55.7%) | 27(44.3%) | 0.855 |
| Moderate | 98 | 52(53.1%) | 46(46.9%) | |
| Poor | 29 | 17(58.6%) | 12(41.4%) | |
| T status | ||||
| T1 | 9 | 9(8.7%) | 0(0.0%) | 0.008* |
| T2 | 14 | 11(10.7%) | 3(3.5%) | |
| T3 | 153 | 77(74.8%) | 76(89.4%) | |
| T4 | 12 | 6(5.8%) | 6(7.1%) | |
| TNM stage | ||||
| I | 20 | 18(90%) | 2(10%) | 0.000* |
| II | 78 | 31(39.7%) | 47(60.3%) | |
| III | 60 | 33(55%) | 27(45%) | |
| IV | 30 | 21(70%) | 9(30%) | |
| Dukes stage | ||||
| A stage | 30 | 21(70%) | 9(30%) | 0.022* |
| B stage | 66 | 27(40.9%) | 39(59.1%) | |
| C stage | 57 | 32(56.1%) | 25(43.9%) | |
| D stage | 35 | 23(65.7%) | 12(34.3%) | |
| Lymph node metastasis | ||||
| N0 | 98 | 39(37.9%) | 59(69.4%) | 0.000* |
| N1 | 90 | 64(62.1%) | 26(30.6%) | |
| M status | ||||
| M0 | 158 | 82(79.6%) | 76(89.4%) | 0.068 |
| M1 | 30 | 21(20.4%) | 9(10.6%) | |
*
P<0.05.