Table 2. Cox regression analysis of prognostic factors for overall CRC patient survival (n=188).

Clinicopathological features	Univariate Analysis		Multivariate Analysis
	HR (95%Cl)	P-value	HR (95%Cl)	P-value
miR-138-5p downregulation	0.466(0.274-0.790)	0.001*	0.493(0.273-0.890)	0.019*
Gender	0.688(0.402-1.176)	0.535
Age	0.677(0.465-1.241)	0.688
T status	1.605(0.969-2.658)	0.066	1.561(0.951-2.564)	0.078
Lymph node metastasis	1.990(1.393-2.841)	<0.001*	1.831(1.296-2.587)	0.001*
M status	2.819(1.632-4.869)	<0.001*	2.65(2.015-4.542)	<0.001*
TNM stage	2.623(1.959-3.512)	<0.001*	2.004(1.384-2.901)	<0.001*
Dukes stage	2.793(2.093-3.728)	<0.001*	2.113(1.492-2.992)	<0.001*

CI = confidence interval; HR = hazard ratio

^*P<0.05.