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. 2016 May 31;7(29):45429–45443. doi: 10.18632/oncotarget.9742

Figure 5. Resistance to 2cPE induced apoptosis correlates with the magnitude of changes in DEGs.

Figure 5

DEGs induced by 2cPE or bortezomib treatments in B-CLL cells were hierarchically clustered as described in the material and methods. In the heat map up-regulated genes are displayed in blue and down-regulated genes in dark green. A colour code was used to represent the apoptotic responsiveness to 2cPE and bortezomib of the different B-CLL cells. Apoptosis >75% (dark green); apoptosis between 46-74% (light green) apoptosis <20% (grey) apoptosis <10% (black).