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. 2016 May 31;7(29):45429–45443. doi: 10.18632/oncotarget.9742

Table 2. GO-Terms enrichment analysis.

Gene enrichment analysis in 2cPE treated primary B-CLL cells
GO-Term Count % p Value Benjamini FDR Fold Enr
GO:0006986~response to unfolded protein 13 8,33 1,66E-12 2,67E-09 2,78E-09 19,82
GO:0051789~response to protein stimulus 13 8,33 3,90E-07 1,96E-07 4,08E-07 13,15
GO:0050865~regulation of cell activation 14 8,97 7,16E-09 3,84E-06 1,20E-05 8,66
GO:0010033~response to organic substance 25 16,02 3,11E-08 1,25E-05 5,21E-05 3,75
GO:0006457~protein folding 13 8,33 7,73E-08 1,75E-05 0,00013 7,94
GO:0042981~regulation of apoptosis 25 16,02 2,38E-07 4,80E-05 0,0004 3,37
Gene enrichment analysis in Bortezomib treated primary B-CLL cells
GO-Term Count % p Value Benjamini FDR Fold Enr
GO:0000502~proteasome complex 14 15,73 4,31E-18 5,26E-16 4,97E-15 42,52
GO:0051351~positive regulation of ligase activity 15 16,85 1,35E-18 1,16E-15 2,09E-15 37,56
GO:0043161~proteasomal protein catabolic process 15 16,85 1,91E-16 1,91E-14 3,44E-13 26,88