Figure 7. AGR2 is overexpressed in patient PDAC tissues, which is in contrast to the reduced expression of miR-1291 (Figure 1B).

(A, B) AGR2 mRNA levels were significantly higher in pancreatic tumor tissues than non-tumor tissues, as determined by selective qPCR analyses. (C) AGR2 protein (brown stains) levels were much higher in patient PDAC than adjunct normal pancreatic tissues, as demonstrated by immunohistochemistry study.