Table 1. Proteins differentially expressed in miR-1291-expressing and control PANC-1 cells, which were identified by 2D-DIGE, MALDI-TOF and MS/MS proteomic profiling study.
| Fold of change (miR-1291/control) | Top Ranked Protein Name (Species) | Gene |
|---|---|---|
| −9.49 | Anterior gradient homolog 2 [Homo sapiens] | AGR2 |
| −7.95 | Argininosuccinate synthase [Homo sapiens] | ASS1 |
| −4.03 | Chain C, Structure Of The H3-H4 Chaperone Asf1Bound To Histones H3 And H4 | ASF1 |
| −2.77 | Ornithine aminotransferase, mitochondrial isoform 1 precursor [Homo sapiens] | OAT |
| −2.50 | Keratin, type II cytoskeletal 8 [Homo sapiens] | KRT8 |
| −2.45 | Phosphoenolpyruvate carboxykinase 2 (mitochondrial) [Homo sapiens] | PCK2 |
| −2.44 | Chain A, The Crystal Structure Of Human Enoyl-Coenzyme A (Coa) Hydratase Short Chain 1, Echs1 | ECHS1 |
| −2.43 | Phosphoserine aminotransferase isoform 1 [Homo sapiens] | PSAT1 |
| −2.41 | Dihydrolipoamide acetyltransferase [Homo sapiens] | DLAT |
| −2.39 | Peroxiredoxin 3, isoform CRA_a [Homo sapiens] | PRDX3 |
| −2.39 | Cysteine-rich protein 2 [Homo sapiens] | CRIP2 |
| −2.32 | Chain C, Human Pcna | PCNA |
| −2.20 | Fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus), isoform CRA a [Homo sapiens] | FSCN1 |
| −2.19 | Serpin H1 precursor [Homo sapiens] | HSP47 |
| −2.15 | Protein disulfide-isomerase precursor [Homo sapiens] | P4HB |
| −2.15 | Chain A, Crystal Structure Of The Protein-Disulfide Isomerase Related Chaperone Erp29 | ERP29 |
| −2.15 | Triosephosphate isomerase isoform 2 [Homo sapiens] | TPI1 |
| −2.07 | Peroxiredoxin-4 [Homo sapiens] | PRDX4 |
| −2.00 | Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial isoform a precursor [Homo sapiens] | IDH3B |
| 2.39 | Superoxide dismutase [Mn], mitochondrial isoform A precursor [Homo sapiens] | SOD2 |
| 3.49 | Nicotinamide phosphoribosyltransferase precursor [Homo sapiens] | NAMPT |
| 3.69 | Chain B, Crystal Structures Of Native And Inhibited Forms Of Human Cathepsin D: Implications For Ly | CTSD |
| 3.92 | Chain A, Cellular Retinoic Acid Binding Protein Ii In Complex With A Synthetic Retinoic Acid (Ro-13) | CRABP2 |
| 5.10 | Cofilin-1 [Homo sapiens] | CFL1 |
| 5.31 | Elongation factor 2 [Homo sapiens] | EEF2 |
| 5.53 | Protein mago nashi homolog [Homo sapiens] | MAGOH |
| 6.58 | UDP-glucose 6-dehydrogenase isoform 1 [Homo sapiens] | UGDH |
| 6.60 | Protein S100-A13 [Homo sapiens] | S100A13 |
| 6.97 | Destrin isoform a [Homo sapiens] | DSTN |
| 7.20 | UDP-glucose 6-dehydrogenase isoform 1 [Homo sapiens] | UGDH |
| 12.4 | Keratin, type I cytoskeletal 19 [Homo sapiens] | KRT19 |
| 26.4 | Chain A, Cellular Retinoic Acid Binding Protein Ii In Complex With A Synthetic Retinoic Acid (Ro-13) | CRABP2 |
The cut-off was 2-fold change.