Table 1. Comparison of tumor formation in wild type and sAC KO mice.

	Wild type	sAC KO
# Mice (N)	15	15
Average mouse weight (in g)	25.3 ± 0.9	24.1 ± 0.4
Total papillomas	20	55 (p < 0.05)
% mice with papillomas	60%	93.3% (p< 0.05)
Papillomas/mouse	1.3 ± 0.4	3.7 ± 1.1 (p < 0.05)
Average papilloma volume (mm3)	10.3 ± 5.5	53.2 ± 19.7 (p < 0.05)
Total papilloma volume in cohort (mm3)	155	798
Total carcinomas	2	11