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. 2016 Jun 15;7(29):45608–45621. doi: 10.18632/oncotarget.10058

Figure 7. KLF4α stimulates proliferation in MDA-MB-231 cells.

Figure 7

(A) Forced over-expression of KLF4α in MDA-MB-231 cells results in changes of the actin network as evidenced by phalloidin (red). Note the prominent cortical actin in KLF4α expressing cells as compared to control. (B) While forced expression in the normal breast cell line MCF10A does not alter cell growth, it does stimulate proliferation in the breast cancer cell lines T47D and MDA-MB-231. Two different assays were used: Top and bottom left panels show the result of counting the cells after the indicated times. The bottom right panel displays BrdU incorporation. *p ≤ 0.05 (KLF4α versus pCMV6).