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. 2016 Jun 13;7(29):45876–45888. doi: 10.18632/oncotarget.9970

Figure 2. Characterization of A2780-VIM-KN, A2780-DR-VIM-OE, HO-8910-VIM-KN cells.

Figure 2

a-b. Western blotting and qPCR analysis confirming that the expression of vimentin was downregulated in A2780-VIM-KN cells and vimentin was overexpressed in A2780-DR-VIM-OE cells as compared to control cells. c. Growth curves of A2780 cells and A2780-DR cells showing that A2780-DR cells grew slower than A2780 cells. d. Growth curves of A2780-VIM-KN and control cells showing A2780-VIM-KN cells grew slower than control cells. e. Growth curves of A2780-DR-VIM-OE and control cells showing A2780-DR-VIM-OE cells grew faster than the control cells. f–g. Survival rates of A2780-VIM-KN, A2780-DR-VIM-OE and their control cells treated with different concentrations of cisplatin. h. Western blotting confirming that the expression of vimentin was downregulated in HO-8910-PM cells. i. Survival rates of HO-8910-PM and HO-8910-PM-VIM-KN cells treated with different concentration of cisplatin for 24 h. j. Growth curves of HO-8910-PM-VIM-KN and control cells showing HO-8910-PM-VIM-KN cells grew slower than control cells. All the results show the means of three independent experiments. Error bars indicate SEM. Data were analyzed using Student's t test. *p < 0.05, **p < 0.01 and ***p < 0.001.