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. 2016 Jun 14;7(29):45959–45975. doi: 10.18632/oncotarget.10009

Table 1. Selectivity of LDC047896 for RON on biochemical and cellular levels in comparison to BMS777607.

Biochemical RON kinase assay IC50[nM] Biochemical cMET kinase assay IC50[nM] Cellular RON inhibition IC50[nM] Cellular cMET inhibition IC50[nM]
LDC047896 21 74 1.6 2000
BMS777607 12 1.4 14 150