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A-D. The CK2 inhibitor, TBB, increases the enrichment of Ikaros (A,C) and H3K4me3 (B,D) in B-ALL cells and patients' samples. The cells were treated with TBB 25μM for 1-2 days and qChIP was performed as described in methods section. E. TBB increases KDM5B binding at the SH2B3 promoter in patient samples.
