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. 2016 Jun 14;7(29):46028–46041. doi: 10.18632/oncotarget.10016

Table 1. Cell cycle phases' distribution in NB4 cells treated with fucoidan, ATO or in combination.

Sub G0/G1 G0/G1 S Mitosis
ATO 0.25 μM Control 1.93 ± 0.3 42.46 ± 1.39 22.34 ± 0.06 31.67 ± 1.34
Fucoidan 18.34 ± 1.75 28.66 ± 1.42 22.38 ± 2.7 29.18 ± 3.38
ATO 2.73 ± 1.08 45.10 ± 0.54 20.22 ± 0.41 30.39 ± 0.87
Combination 20.69 ± 1.54 31.30 ± 0.09 25.8 ± 2.68 19.44 ± 2.04
ATO 0.5 μM Control 1.93 ± 0.3 42.46 ± 1.39 22.34 ± 0.06 31.67 ± 1.34
Fucoidan 18.34 ± 1.75 28.66 ± 1.42 22.38 ± 2.7 29.18 ± 3.38
ATO 2.39 ± 1.08 46.10 ± 0.54 20.22 ± 0.41 29.39 ± 0.87
Combination 25.57 ± 0.86 38.42 ± 1.38 15.20 ± 0.34 18.14 ± 1.66
ATO 1.0 μM Control 1.93 ± 0.3 42.46 ± 1.39 22.34 ± 0.06 31.67 ± 1.34
Fucoidan 18.34 ± 1.75 28.66 ± 1.42 22.38 ± 2.7 29.18 ± 3.38
ATO 15.13 ± 0.4 39.81 ± 3.82 16.56 ± 0.8 25.50 ± 2.11
Combination 74.51 ± 2.26 7.29 ± 1.36 9.28 ± 2.28 6.76 ± 0.7

NB4 cells were treated with with low and therapeutic doses of ATO with or without fucoidan (20 μg/ml) and cell cycle was analyzed after 48 hours. Data represents Mean±SEM of three replicates.