Table 3. Univariate and multivariable Cox regression analyses for disease free survival.
| Factor | Univariate analysis | Multivariate analysis | ||||
|---|---|---|---|---|---|---|
| HR | 95%Cl | P-value | HR | 95%Cl | P-value | |
| Disease-free survival | ||||||
| Age(<60/>=60) | 1.421 | (0.807 to 2.502) | 0.216 | |||
| Gender(male/female) | 0.736 | (0.418 to 1.296) | 0,281 | |||
| Location(colon/rectum) | 0.880 | (0.503 to 1.538) | 0.651 | |||
| Tumor size(<5cm/>=5cm) | 1.290 | (0.752 to 2.213) | 0.359 | |||
| CEA(normal/elevated) | 1.495 | (0.873 to 2.558) | 0.147 | |||
| Grade of differentiation (well/poor) | 1.678 | (0.960 to 2.934) | 0.078 | |||
| TNM stage (I-II/III-IV) | 2.081 | (1.203 to 3.599) | 0.008* | 1.823 | (1.052 to 3.160) | 0.032* |
| B. fragilis (low/high) | 2.673 | (1.504 to 4.751) | 0.001* | 2.042 | (1.116 to 3.738) | 0.021* |
| F. prausnitzii (low/high) | 0.696 | (0.406 to 1.194) | 0.185 | |||
| F. nucleatum (low/high) | 2.478 | (1.395 to 4.404) | 0.001* | 1.829 | (1.000 to 3.345) | 0.050* |
HR relative risk, 95% CI 95% confidence interval.
*
statistically significant P<0.05, Cox proportional hazard regression model.