Table 2. Estimates of BCSS and OS and pairwise comparisons according to tumor size and lymph node status.
Tumor size/nodal status | No. of patients | BCSS | OS | ||||||
---|---|---|---|---|---|---|---|---|---|
No. of events | Overall Pa | Pairwise | Adjusted Pb | No. of events | Overall Pa | Pairwise | Adjusted Pb | ||
Total | 10771 | 337 | <0.001 | N0 v N1 | 0.133 | 547 | <0.001 | N0 v N1 | 0.011 |
N0 | 7481 | 115 | N0 v N2 | 0.654 | 234 | N0 v N2 | 0.785 | ||
N1 | 2355 | 130 | N0 v N3 | 0.377 | 177 | N0 v N3 | 0.999 | ||
N2 | 562 | 38 | N1 v N2 | 1.000 | 63 | N1 v N2 | 0.916 | ||
N3 | 373 | 54 | N1 v N3 | 0.002 | 73 | N1 v N3 | 0.054 | ||
N2 v N3 | 0.053 | N2 v N3 | 0.729 | ||||||
T1 | <0.001 | N0 v N1 | 0.984 | <0.001 | N0 v N1 | 0.114 | |||
Total | 5292 | 76 | N0 v N2 | 0.944 | 151 | N0 v N2 | 0.999 | ||
N0 | 4343 | 37 | N0 v N3 | 0.865 | 93 | N0 v N3 | 1.000 | ||
N1 | 747 | 25 | N1 v N2 | 0.998 | 35 | N1 v N2 | 0.874 | ||
N2 | 130 | 6 | N1 v N3 | 0.610 | 12 | N1 v N3 | 0.836 | ||
N3 | 72 | 8 | N2 v N3 | 0.592 | 11 | N2 v N3 | 1.000 | ||
T2 | <0.001 | N0 v N1 | 0.138 | <0.001 | N0 v N1 | 0.248 | |||
Total | 4640 | 178 | N0 v N2 | 0.678 | 280 | N0 v N2 | 0.963 | ||
N0 | 2825 | 62 | N0 v N3 | 1.000 | 112 | N0 v N3 | 1.000 | ||
N1 | 1294 | 75 | N1 v N2 | 1.000 | 102 | N1 v N2 | 0.986 | ||
N2 | 327 | 26 | N1 v N3 | 0.542 | 39 | N1 v N3 | 0.874 | ||
N3 | 194 | 15 | N2 v N3 | 0.829 | 27 | N2 v N3 | 0.999 | ||
T3 | <0.001 | N0 v N1 | 0.841 | <0.001 | N0 v N1 | 0.854 | |||
Total | 839 | 83 | N0 v N2 | 1.000 | 116 | N0 v N2 | 0.931 | ||
N0 | 313 | 16 | N0 v N3 | 0.987 | 29 | N0 v N3 | 0.993 | ||
N1 | 314 | 30 | N1 v N2 | 0.993 | 40 | N1 v N2 | 1.000 | ||
N2 | 105 | 6 | N1 v N3 | 0.190 | 12 | N1 v N3 | 0.375 | ||
N3 | 107 | 31 | N2 v N3 | 0.987 | 35 | N2 v N3 | 0.670 |
Overall P was calculated using the Kaplan-Meier method and the log-rank test, and bold type indicates significance.
Adjusted P was calculated using Sidak pairwise comparisons, and bold type indicates significance.