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. 2016 May 18;7(29):46636–46645. doi: 10.18632/oncotarget.9432

Table 3. Multivariate Cox proportional hazard model for assessing outcome-related factors.

Variable BCSS OS
HR 95% CI Pc HR 95% CI Pc
Age (years)
≥50 1 1
<50 0.974 0.778-1.218 0.815 0.773 0.643-0.929 0.006
Race 0.144 0.029
White 1 1
Black 1.051 0.811-1.362 0.709 1.047 0.855-1.283 0.655
Othera 0.606 0.359-1.023 0.061 0.569 0.370-0.876 0.010
Marital status
Married 1 1
Not marriedb 1.144 0.915-1.427 0.234 1.269 1.067-1.508 0.007
Grade
III 1 1
I/II 0.697 0.490-0.994 0.046 0.882 0.690-1.128 0.316
Tumor size <0.001 <0.001
T1 1 1
T2 1.884 1.427-2.487 <0.001 1.644 1.338-2.019 <0.001
T3 3.735 2.653-5.259 <0.001 3.032 2.322-3.959 <0.001
Lymph node status <0.001 <0.001
N0 1 1
N1 2.836 2.182-3.686 <0.001 2.024 1.650-2.482 <0.001
N2 3.311 2.260-4.850 <0.001 2.940 2.199-3.931 <0.001
N3 7.725 5.464-10.922 <0.001 5.599 4.228-7.415 <0.001
Type of surgery <0.001 <0.001
Breast-conserving surgery 1 1
Mastectomy 1.167 0.902-1.510 0.240 1.208 0.986-1.480 0.069
None 2.810 1.800-4.387 <0.001 3.067 2.179-4.317 <0.001
Radiation therapy
No 1 1
Yes 0.659 0.520-0.835 0.001 0.582 0.481-0.704 <0.001

Abbreviation: CI, confidence interval.

a

Other includes American Indian/native Alaskan and Asian/Pacific Islander.

b

Not married includes divorced, separated, single (never married), unmarried or domestic partner and widowed.

c

P values were adjusted using a multivariate Cox proportional hazard regression model including all factors, as categorized in Table 3, and bold type indicates significance.