Table 2. Biomarkers to predict response to anti-VEGF inhibitors.
Functional imaging |
Hypertension |
Circulating proteins (baseline plasma VEGF concentration and soluble VEGFR-2) |
Circulating endothelial or tumor cells |
Single nucleotide polymorphisms (SNPs) |
Tumor biomarkers (CD31-positive tumor vessels; Tumor neuropilin 1 immunoreactivity; plasma levels of intercellular adhesion molecule-1) |