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. 2016 Apr 18;7(29):46750–46767. doi: 10.18632/oncotarget.8775

Table 3. FGFR2 translocations in ICC.

Study No. of patients (n) No. of patients with FGFR2 translocation (n, %) Type of FGFR2 Translocations Method
Wu et al. [59] 2 2 (100%) FGFR2-BICC1 RNA, exome sequencing
Borad et al. [30] 6 3 (50%) FGFR2-TACC3
FGFR2-BICC1
FGFR2-MGEA5
Genome-wide and whole transcriptome sequencing
Graham et al. [29] 96 12 (13%) NR Fluorescence in situ hybridization
Arai et al. [28] 66 9 (13.6%) FGFR2-AHCYL1
FGFR2-BICC1
Whole transcriptome sequencing
Ross et al.[17] 28 3 (10.7%) FGFR2-KIAA1598
FGFR2-BICC1
FGFR2-TACC3
Next generation sequencing
Sia et al. [31] 107 48 (45%) FGFR2-PPHLN1
FGFR2-BICC1
RNA, exome sequencing
Nakamura et al. [60] 109 6 (5.5%) FGFR2-KCTD1
FGFR2-TXLNA
FGFR2-BICC1(Type 2)
Exome sequencing

Abbreviations: NR, Not reported