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. 2016 Apr 18;7(29):46768–46784. doi: 10.18632/oncotarget.8776

Figure 1. Light, suprachiasmatic nuclei (SCN), and the pineal/melatonin circuit.

Figure 1

Melanopsin in retinal ganglion cells in the eye respond to light (natural or artificially) and transmit signals to the SCN. Then light-induced activation of the SCN prevents the pineal gland from producing melatonin and; conversely, melatonin production and secretion is increased during the dark period.